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患者，男性，60岁。因慢性阻塞性肺疾病并发呼吸衰竭、肺性脑病予气管插管机械通气，病情一度改善。但瞬间病情突然恶化，躁动、发绀加重。呼吸监测表明气道阻力轻度增高，肺顺应性明显降低，其最可能的原因是（）
A . 呼吸道分泌物引流不畅
B . 并发气胸
C . 肺水肿
D . 肺栓塞
E . 急性左心衰竭
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